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Houston Astros vs. Cleveland Guardians odds, tips and betting trends | May 25

In the final game of a three-game series at Minute Maid Park, the Cleveland Guardians (18-21) face the Houston Astros (28-16), Wednesday at 8:10 PM ET.

The Astros are favored (-185 moneyline odds to win) when they take on the Guardians (+159). The matchup on the mound for this contest is set with the Houston Astros looking to Cristian Javier (2-2), and Cal Quantrill (1-2) getting the nod for the Cleveland Guardians.

These teams meet again after the Astros beat the Guardians 7-3 yesterday. Framber Valdez picked up the win for the Astros (7.0 IP, 3 R, 7 H, 4 K), and Kyle Tucker led the way offensively (1-for-4 with a home run and three RBI). Zach Plesac (4.2 IP, 7 R, 9 H, 5 K) was credited with the loss for the Guardians.

Before watching this Astros vs. Guardians matchup, here is everything you need to know about Wednesday’s action on the diamond.

Houston Astros vs. Cleveland Guardians Odds and Betting Lines

Major League Baseball odds courtesy of Tipico Sportsbook. Odds updated Wednesday at 2:05 AM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Favorite: Astros (-185, bet $185 to win $100)
  • Underdog: Guardians (+159, bet $100 to win $159)
  • Over/under: 8

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Astros Stats and Trends

Astros Betting Records

  • The Astros have won 24, or 70.6%, of the 34 games they’ve played as favorites this season.
  • Houston has been at least a -185 moneyline favorite eight times this season and won each of those games.
  • The implied probability of a win from the Astros, based on the moneyline, is 64.9%.
  • Games involving Houston have gone over the total set by oddsmakers in 12 of 44 chances this season.
  • The Astros are 23-21-0 against the spread this season.

Cristian Javier (Astros Probable Starter)

  • The Astros’ Javier (2-2) will make his fifth start of the season.
  • The right-hander’s last appearance was on Saturday, when he threw six innings against the Texas Rangers, giving up one earned run while allowing three hits.
  • The 25-year-old has pitched in eight games this season with a 2.87 ERA and 11.2 strikeouts per nine innings with a batting average against of .200.
  • The Guardians rank 17th in MLB with 180 runs scored this season. They have a .245 batting average this campaign with 36 home runs (22nd in the league).

Astros Batting Stats

  • The Astros have hit 59 homers this season, which ranks third in the league.
  • Hitters for the Astros have a combined .409 slugging percentage this season, which ranks fifth in MLB.
  • Houston has a team batting average of .230 this season, which ranks 22nd among MLB teams.
  • The Astros rank 12th in the league with 188 total runs scored this season.
  • Houston has an OBP of .308 this season, which ranks 17th in MLB.
  • The Astros have shown patience at the plate this season with the 10th-best rate of strikeouts per game (7.8) among MLB offenses.

Guardians Stats and Trends

Guardians Betting Records

  • The Guardians have been victorious in 13, or 44.8%, of the 29 contests they have been chosen as underdogs in this season.
  • Cleveland has a win-loss record of 2-5 when favored by +159 or worse by oddsmakers this year.
  • Bookmakers have implied with the moneyline set for this matchup that the Guardians have a 38.6% chance of pulling out a win.
  • Cleveland and its opponents have gone over the total this season in 23 of their 43 opportunities.
  • The Guardians have an against the spread record of 21-22-0 in 43 games with a line this season.

Cal Quantrill (Guardians Probable Starter)

  • Quantrill makes the start for the Guardians, his eighth of the season. He is 1-2 with a 3.48 ERA and 25 strikeouts through 41 1/3 innings pitched.
  • In his last outing on Thursday against the Cincinnati Reds, the right-hander went seven innings, allowing one earned run while surrendering five hits.
  • The 27-year-old has an ERA of 3.48, with 5.4 strikeouts per nine innings in seven games this season. Opponents are hitting .231 against him.
  • Quantrill is trying to pick up his fifth quality start of the year in this outing.
  • Quantrill will try to prolong a six-game streak of lasting five or more innings (he’s averaging 5.3 frames per outing).
  • He will face off against an Astros offense that ranks 16th in the league with 334 total hits (on a .230 batting average). The squad also slugs a collective .409 (fifth in the league) with 59 total home runs (third in MLB play).
  • Among qualifying pitchers in MLB play this season, the 27-year-old’s 3.48 ERA ranks 31st, 1.185 WHIP ranks 35th, and 5.4 K/9 ranks 56th.

Guardians Batting Stats

  • The Guardians average 0.9 home runs per game to rank 22nd in MLB play with 36 total home runs .
  • So far this season, the Guardians’ .391 slugging percentage ranks 12th in the league.
  • Cleveland’s .245 batting average is ninth-best in MLB.
  • Averaging 4.6 runs per game (180 total), the Guardians are the 17th-highest scoring team in baseball.
  • Cleveland is 16th in baseball with a .310 on-base percentage.
  • The Guardians strike out the least in baseball, averaging 7.3 per game.

Place your legal, online sports bets in CO and NJ at Tipico Sportsbook now.

Astros vs. Guardians: Live Streaming Info & Game Time

  • Game Day: Wednesday, May 25, 2022
  • Game Time: 8:10 PM ET
  • Stadium: Minute Maid Park
  • TV Channel: AT&T Sportsnet Southwest
  • Live Stream: fuboTV (Watch for free)

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