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Boston Celtics at Cleveland Cavaliers odds, picks and prediction

Apr 6, 2021; Boston, Massachusetts, USA; Boston Celtics forward Jayson Tatum (0) drives to the basket against the Philadelphia 76ers in the second quarter at TD Garden. Mandatory Credit: David Butler II-USA TODAY Sports

The Boston Celtics (35-34) travel to meet the Cleveland Cavaliers (21-48) Wednesday at Rocket Mortgage FieldHouse. Tip-off is set for 8 p.m. ET. Below, we analyze the Celtics vs. Cavaliers odds and lines, with NBA picks and predictions.

The Celtics have dropped three in a row, including a back-to-back set against the Miami Heat. Boston was outscored by an average of 122.5 PPG to 129.5 PPG in the two-game sweep at the hands of Miami.

The Cavaliers were put up a good fight Monday against the Pacers, but they again came up short 111-102 as they pushed against the number. They have lost 11 consecutive games while going 0-10-1 ATS. The nine-point loss snapped a six-game run of losses by 16 or more points.

Celtics at Cavaliers: Odds, spread and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 7:10 a.m. ET.

  • Money line: Celtics -550 (bet $550 to win $100) | Cavaliers +400 (bet $100 to win $400)
  • Against the spread/ATS: Celtics -10.5 (-110) | Cavaliers +10.5 (-110)
  • Over/Under: 219.5 (O: -110 | U: -110)

Celtics at Cavaliers: Key injuries

Celtics

  • SG Jaylen Brown (wrist) out
  • C Robert Williams III (toe) out

Cavaliers

  • PG Matthew Dellavedova (neck) out
  • PG Darius Garland (ankle) out
  • C Isaiah Hartenstein (concussion) out
  • PF Larry Nance Jr. (thumb) out
  • SF Cedi Osman (ankle) questionable
  • SF Taurean Prince (ankle) out
  • PF Lamar Stevens (concussion) out
  • SG Dylan Windler (knee) out

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Celtics at Cavaliers: Odds, lines, predictions and picks

Prediction

Celtics 117, Cavaliers 109

Money line (ML)

The Celtics (-550) will cost you five-and-a-half times your potential return, and that’s ridiculous risk for a road team.

AVOID.

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Against the spread (ATS)

The CAVALIERS +10.5 (-110) should be able to keep this one within single digits, as they put up a spirited effort against Indiana last time out. The Celtics -10.5 (-110) have failed to cover in each of the past three, they’re 1-5 ATS in the past six and 2-8 ATS over the previous 10. That makes Cleveland worth a small-unit play.

Over/Under (O/U)

OVER 219.5 (-110) is the play here. Boston has hit the Over in eight of the past nine games, while the Over is 4-2 across the past six for Cleveland. The Over is also 4-1 in the past five at home for the Cavs.

Want some action on this one? Place a bet at BetMGM now. For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

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