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Houston Astros at New York Yankees odds, picks and prediction

Apr 17, 2021; Seattle, Washington, USA; Houston Astros starting pitcher Zack Greinke (21) throws against the Seattle Mariners during the first inning at T-Mobile Park. Mandatory Credit: Joe Nicholson-USA TODAY Sports

The Houston Astros (15-13) and New York Yankees (14-14) open a three-game series Tuesday at Yankee Stadium. First pitch is scheduled for 7:05 p.m. ET (on ESPN). Let’s analyze BetMGM Sportsbook‘s lines around the Astros vs. Yankees odds with MLB picks and predictions.

This is the first meeting between the two clubs since the Astros eliminated the Yankees 4 games to 2 in the 2019 best-of-7 AL Championship Series.

Both teams had Monday off. The Astros lost 5-4 at the Tampa Bay Rays Sunday after taking the first two of the series. The Yankees shut out the visiting Detroit Tigers 2-0 Sunday to complete a 3-game sweep for their third win in a row.

RHP Zack Greinke is Houston’s projected starter for the opener. The 18-year veteran is 2-1 with a 3.44 ERA (36 2/3 IP, 14 ER), 1.15 WHIP, 6.6 K/9 and 1.5 BB/9 in 6 starts this season.

  • Last outing: No-decision, 4 IP, 4 ER, 4 H, 2 BB, 5 K vs. Seattle Mariners Wednesday – Astros won 7-5
  • Career vs. Yankees (regular season): 4-4, 5.05 ERA (71 1/3 IP, 40 ER), 1.33 WHIP, 6.9 K/9 in 12 starts and 3 relief appearances

RHP Domingo German is slated to start for New York. He is 2-2 with a 4.05 ERA (20 IP, 9 ER), 1.30 WHIP, 8.6 K/9 and 1.8 BB/9 in 4 starts.

  • Last outing: Win, 7 IP, 0 ER, 3 H, 1 BB, 6 K in 7-0 shutout at Baltimore Orioles Wednesday
  • Career vs. Astros: 0-1, 3.86 ERA (11 2/3 IP, 5 ER), 13 H, 3 BB, 12 K in 3 games, including 1 start

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Astros at Yankees odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 7:20 a.m. ET.

  • Money line: Astros +100 (bet $100 to win $100) | Yankees -120 (bet $120 to win $100)
  • Against the spread/ATS: Astros -1.5 (+155) | Yankees +1.5 (-190)
  • Over/Under: 9 (O: -105 | U: -115)

Prediction

Astros 4, Yankees 2

Money line (ML)

HOUSTON (+100) is the STRONGEST PLAY – 1½ times your usual wager. Not only are the Astros 5-1 in Greinke’s starts, they are the better offensive team. They’re scoring 4.93 runs per game and hitting .253 to rank 2nd and 4th, respectively, in the AL.

The Yankees average 3.93 runs per game with a .221 batting average to rank 13th and 11th in the AL, respectively.

Sure, German is coming off one of the best starts of his career, but it was against the Orioles, who average 3.82 runs per game (14th in AL) with a .228 batting average (9th).

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Run line/Against the spread (ATS)

Back HOUSTON -1.5 (+155) with a HALF-UNIT wager. The Astros’ last six wins were by at least 2 runs.

ATS records: Astros 14-14 | Yankees 13-15

Over/Under (O/U)

UNDER 9 (-115) is the play. Thanks to New York’s offensive struggles, the Under is 9-5 at Yankee Stadium this season.

The Under is also 3-1 in German’s starts; it’s 3-3 when Greinke takes the hill for Houston.

O/U records: Astros 15-12-1 | Yankees 10-18

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Bet on this game now at BetMGM Sportsbook. For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

JOHNNY’S RECORD W-L SP ROI
2021 MLB 35-31-1 9-10-1 -0.12
2020 MLB 80-59-1 39-21 +24.79
2021 (all sports) 138-116-2 58-51-1 +13.43
*SP: Strongest plays; ROI: Return on investment

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